PRIMARY STUDY
Effects of cannabinoid receptor activation by CP55,940 on normal bladder function and irritation-induced bladder overactivity in non-awake anaesthetised rats
Key Findings: Key findings demonstrate that a synthetic analogue of THC reverses urinary frequency in overactive bladder syndrome, which suggests it may be effective in treating lower urinary tract symptoms.
Type of Study: Animal Study
Study Result: Positive
Research Location(s): United Kingdom
Year of Pub: 2016
Cannabinoids Studied: CP-x Synthetic Cannabinoids
Phytocannabinoid Source: Not Applicable
Receptors Studied: CB1, CB2
Route of Administration: Injection
Citation: Bakali E, et al. Effects of cannabinoid receptor activation by CP55,940 on normal bladder function and irritation-induced bladder overactivity in non-awake anaesthetised rats. Int Urogynecol J. 2016; 27:1393-400. doi: 10.1007/s00192-016-2984-x
Authors: Bakali E, Mbaki Y, Lambert DG, Elliott RA, Mason R, Tincello DG
