PRIMARY STUDY
Evaluation of selective cannabinoid CB(1) and CB(2) receptor agonists in a mouse model of lipopolysaccharide-induced interstitial cystitis
Key Findings: These findings strongly suggest that modulation of the cannabinoid CB2 receptors might be a promising therapeutic strategy for the treatment of bladder diseases and conditions characterized by inflammation, such as interstitial cystitis. More specifically, the use of JWH015 (CB2 agonist) induced anti-inflammatory activity in the test animals.
Type of Study: Animal Study
Study Result: Positive
Research Location(s): Italy
Year of Pub: 2014
Cannabinoids Studied: JWH-x Synthetic Cannabinoids
Phytocannabinoid Source: Not Applicable
Receptors Studied: CB2
Citation: Tambaro S, et al. Evaluation of selective cannabinoid CB(1) and CB(2) receptor agonists in a mouse model of lipopolysaccharide-induced interstitial cystitis. Eur J Pharmacol. 2014; 729:67-74. doi: 10.1016/j.ejphar.2014.02.013
Authors: Tambaro S, Casu MA, Mastinu A, Lazzari P
