Key Findings:  This study demonstrates that cannabigerolic acid confers superior renoprotective effects compared to cannabidiol in models of acute and chronic kidney injury by suppressing inflammation, apoptosis, and fibrosis—potentially via TRPM7 inhibition—while both cannabinoids reduce renal fibrosis and caspase-3 activity.
Type of Study:  Animal Study
Study Result:  Positive
Research Location(s):  United States
Year of Pub:  2026
Cannabinoids Studied:  Cannabidiol (CBD), Cannabigerol (CBG)
Phytocannabinoid Source:  Not Applicable
Ligands Studied:  Pro-inflammatory cytokines
Route of Administration:  , Injection
Citation:  Suzuki S, Fleig A, Penner R. CBGA ameliorates inflammation and fibrosis in nephropathy. Sci Rep. 2023 Apr 18;13(1):6341. doi: 10.1038/s41598-023-33507-2. PMID: 37072467; PMCID: PMC10113213.