PRIMARY STUDY

The renoprotective effects of cannabidiol on lipopolysaccharide-induced systemic inflammation model of rats

Key Findings:  In this rat model of sepsis, cannabidiol (CBD) induced a positive shift in the oxidative balance, showing protective properties against kidney damage, and promise as a novel therapeutic agent for the treatment of sepsis.

Type of Study:  Animal Study

Study Sample Size:  32

Study Result:  Positive

Research Location(s):  Turkey

Year of Pub:  2024


Cannabinoids Studied:  Cannabidiol (CBD), Pharma CBD

Phytocannabinoid Source:  Not Applicable

Chemotype:  Chemotype III




Citation:  İlhan İ, Asci H, Ozmen O, Buyukbayram Hİ, Arlıoglu M, Kurtbolat O. The renoprotective effects of cannabidiol on lipopolysaccharide-induced systemic inflammation model of rats. Naunyn Schmiedebergs Arch Pharmacol. 2025 Feb;398(2):1841-1851. doi: 10.1007/s00210-024-03391-2. Epub 2024 Aug 24. PMID: 39180672.