PRIMARY STUDY

Urinary fatty acid and retinol binding protein-4 predict CKD progression in severe NAFLD patients with hypertension: 4-year study with clinical and experimental approaches

Key Findings:  This analysis of severe non-alcoholic fatty liver disease (NAFLD) patients with hypertension and proteinuria found that high body mass index, high hepatic fibrosis score, high urinary level of vascular cell adhesion molecule-1, high urinary levels of fatty acid-binding protein (FABP), and high urinary level of retinol binding protein (RBP4) were useful predictors for progressive chronic kidney disease (CKD) during 24 months.

Type of Study:  Meta-analysis

Study Sample Size:  90

Study Result:  Positive

Research Location(s):  Taiwan

Year of Pub:  2020


Cannabinoids Studied:  Fatty Acid-Binding Protein (FABP)

Phytocannabinoid Source:  Not Applicable




Citation:  Tsai YL, Liu CW, Huang SF, Yang YY, Lin MW, Huang CC, Li TH, Huang YH, Hou MC, Lin HC. Urinary fatty acid and retinol binding protein-4 predict CKD progression in severe NAFLD patients with hypertension: 4-year study with clinical and experimental approaches. Medicine (Baltimore). 2020 Jan;99(2):e18626. doi: 10.1097/MD.0000000000018626. PMID: 31914044; PMCID: PMC6959901.