PRIMARY STUDY

Fetal Cannabinoid Syndrome: Behavioral and Brain Alterations of the Offspring Exposed to Dronabinol during Gestation and Lactation

Key Findings:  Mice exposed to dronabinol (THC) exhibited increased anxiety and depressive-like behaviors, as well as cognitive impairments linked to changes in neurodevelopment-related gene and protein expression. Additionally, prenatal and early postnatal THC exposure disrupted the reward system, leading to greater motivation for alcohol consumption in offspring.