PRIMARY STUDY

Evaluation of prevalent phytocannabinoids in the acetic acid model of visceral nociception

Key Findings:  Using the acetic acid stretching test, a rodent visceral pain model, to assess the antinociceptive effects of other phytocannabinoids. The antinociceptive effects of Delta(9)-THC and cannabinol (CBN) occurred at lower doses than those necessary to produce locomotor suppression. This provides evidence that motor dysfunction does not account for the decreases in acetic acid-induced abdominal stretching.