Key Findings:  This analysis of the use of medicinal cannabis for the treatment of Prakinson's disease found that phytocannabinoids improved locomotor activity and involuntary movement and reduced catalepsy.
Type of Study:  Meta-analysis
Study Sample Size:  23
Study Result:  Positive
Study Location(s):  Brazil
Year of Pub:  2024
Cannabinoids Studied:  Cannabidiol (CBD), Tetrahydrocannabinol (THC), WIN-x Synthetic Cannabinoids, Fatty Acid Amide Hydrolase (FAAH), Tetrahydrocannabivarin (THCV)
Phytocannabinoid Source:  Not Applicable
Chemotype:  Chemotype I, Chemotype III
Receptors Studied:  GPCR 55, TRPV1
Ligands Studied:  Dopamine, Serotonin
DOSING DETAILS   
Study Dosing Objective:  Effective Dose,
Established Protocol:  Effective dose
Route of Administration:  Injection, Oral (Ingestion)
Cannabinoid Ratio:  (CBD)   0    
Dosage Form:  Cannabidiol administered intraperitoneally
Dosing Regimen:  Cannabidiol 30 mg/kg
Treatment Duration:  14 days