Key Findings:  Looking at resting state functional connectivity on neuroimaging, this systematic review finds that cannabis and cannabinoids can change functional connectivity in the human brain based on the type of cannabinoid exposure.
Type of Study:  Clinical Meta-analysis
Study Sample Size:  318
Study Result:  Inconclusive
Research Location(s):  Australia, United Kingdom
Year of Pub:  2023
Cannabinoids Studied:  Cannabidiol (CBD), Tetrahydrocannabinol (THC), Cannabinoid (unspecified), Tetrahydrocannabivarin (THCV), Cannabidivarin (CBDV)
Phytocannabinoid Source:  Unspecified
Chemotype:  Chemotype I, Chemotype III
Route of Administration:  Inhalation
Citation:  Lorenzetti V, et al. Effects of cannabinoids on resting state functional brain connectivity: A systematic review. Neurosci Biobehav Rev. 2023; 145:105014. doi: 10.1016/j.neubiorev.2022.105014
Authors:  Lorenzetti V, Gaillard A, Thomson D, Englund A, Freeman TP