Key Findings:  To study the urinary excretion level of 7 different metabolites of ∆9-tetrahydrocannabinol (∆9-THC), subjects were given either oral and vaporized cannabis or a placebo, at differing doses. Results suggest that additional analytes, not just standard ∆9-THC-COOH, may be worth investigating to elucidate better licit versus illicit cannabis consumption.
Type of Study:  Double Blind Clinical Trial
Study Sample Size:  21
Study Result:  Inconclusive
Research Location(s):  United States
Year of Pub:  2022
Cannabinoids Studied:  Cannabidiol (CBD), Tetrahydrocannabinol (THC), Cannabinol (CBN), Tetrahydrocannabivarin (THCV), Delta-8-THC
Phytocannabinoid Source:  Unspecified
Chemotype:  Chemotype I
Dosage: THC low (5–10 mg) THC high (20–25 mg)
Route of Administration:  Inhalation, Oral (Ingestion)
Citation:  Sholler DJ, et al. Urinary Excretion Profile of Cannabinoid Analytes Following Acute Administration of Oral and Vaporized Cannabis in Infrequent Cannabis Users. J Anal Toxicol. 2022; 46:882-890. doi: 10.1093/jat/bkac042
Authors:  Sholler DJ, Zamarripa CA, Spindle TR, Martin EL, Kuntz D, Vandrey R, Grabenauer M