RELATED STUDY
A Review on the Bioactivity of Cannabinoids on Zebrafish Models: Emphasis on Neurodevelopment
Key Findings: This review concludes that zebrafish may prove a useful model for cannabinoid exposure studies. Also emphasized is the need for research into the full spectrum of cannabinoids, beyond the better-known cannabidiol (CBD)and ∆9-tetrahydrocannabinol (THC), as well as studies looking at the mechanism of cannabinoids and the endocannabinoid system and their role in neurological disorders.
Type of Study: Meta-analysis
Study Result: Positive
Research Location(s): Italy
Year of Pub: 2022
Cannabinoids Studied: Cannabichromene (CBC), Cannabidiol (CBD), Cannabigerol (CBG), Tetrahydrocannabinol (THC), Cannabinol (CBN), CP-x Synthetic Cannabinoids, AM-x Synthetic Cannabinoids, JWH-x Synthetic Cannabinoids, WIN-x Synthetic Cannabinoids, Anandamide (AEA), Cannabinoid (unspecified), Endocannabinoid (unspecified), Pharma THC, Pharma CBD, Tetrahydrocannabivarin (THCV), Cannabidivarin (CBDV)
Phytocannabinoid Source: Unspecified
Receptors Studied: CB1, CB2, GPCR 18, GPCR 55, TRPs
Ligands Studied: GABA, Oxytocin, Serotonin
Citation: Licitra R, et al. A Review on the Bioactivity of Cannabinoids on Zebrafish Models: Emphasis on Neurodevelopment. Biomedicines. 2022; 10:(unknown pages). doi: 10.3390/biomedicines10081820
Authors: Licitra R, Marchese M, Naef V, Ogi A, Martinelli M, Kiferle C, Fronte B, Santorelli FM
