PRIMARY STUDY
Specific Compositions of Cannabis sativa Compounds Have Cytotoxic Activity and Inhibit Motility and Colony Formation of Human Glioblastoma Cells In Vitro
Key Findings: In glioblastoma multiform (GBM) cells, (a model for glioma brain tumors), certain cannabis compounds and fractions prevented GBM neurospheres from forming and also induced cell death suggesting potential therapeutic uses in the treatment of highly resistant glioblastoma multiforme.
Type of Study: Laboratory Study
Study Result: Positive
Study Location(s): Israel, United States
Year of Pub: 2021
Cannabinoids Studied: Cannabidiol (CBD), Cannabigerol (CBG), Tetrahydrocannabinol (THC), Cannabinol (CBN), AM-x Synthetic Cannabinoids, SR-x Synthetic Cannabinoids, Tetrahydrocannabivarin (THCV)
Phytocannabinoid Source: Cannabis Flower derived
Receptors Studied: CB1, CB2, TRPA1, TRPV1, TRPV2
