RELATED STUDY

Phytocannabinoids promote viability and functional adipogenesis of bone marrow-derived mesenchymal stem cells through different molecular targets

Key Findings:  Resulting data revealed that CBD, CBDA, CBGA and THCV promote viability of marrow-derived mesenchymal stem cells (BM-MSCs). In addition, CBG and CBD alone or in combination was found to promote BM-MSCs maturation into adipocytes via distinct molecular mechanisms.

Type of Study:  Laboratory Study

Study Result:  Positive

Research Location(s):  Canada, Italy

Year of Pub:  2020


Cannabinoids Studied:  Cannabidiol (CBD), Cannabigerol (CBG), Cannabidiolic Acid (CBD-a), Cannabigerolic Acid (CBG-a), Tetrahydrocannabivarin (THCV)

Phytocannabinoid Source:  Unspecified

Route of Administration:  In vitro




Citation:  Fellous T, et al. Phytocannabinoids promote viability and functional adipogenesis of bone marrow-derived mesenchymal stem cells through different molecular targets. Biochem Pharmacol. 2020; 175:113859. doi: 10.1016/j.bcp.2020.113859

Authors:  Fellous T, De Maio F, Kalkan H, Carannante B, Boccella S, Petrosino S, Maione S, Di Marzo V, Iannotti FA