PRIMARY STUDY

Validation of a liquid chromatography tandem mass spectrometry (LC-MS/MS) method to detect cannabinoids in whole blood and breath

Key Findings:  Using a liquid chromatography tandem mass spectrometry this study confirmed a robust and adequately quantified method that will be used to identify cannabinoid concentrations in biological blood and breath samples.

Type of Study:  Laboratory Study

Study Result:  Positive

Research Location(s):  South Korea, United States

Year of Pub:  2020


Cannabinoids Studied:  Cannabidiol (CBD), Tetrahydrocannabinol (THC), Cannabinol (CBN), Tetrahydrocannabivarin (THCV)

Phytocannabinoid Source:  Not Applicable

Route of Administration:  In vitro




Citation:  Hubbard JA, et al. Validation of a liquid chromatography tandem mass spectrometry (LC-MS/MS) method to detect cannabinoids in whole blood and breath. Clin Chem Lab Med. 2020; 58:673-681. doi: 10.1515/cclm-2019-0600

Authors:  Hubbard JA, Smith BE, Sobolesky PM, Kim S, Hoffman MA, Stone J, Huestis MA, Grelotti DJ, Grant I, Marcotte TD, Fitzgerald RL