RELATED STUDY
Differential Interactions of Selected Phytocannabinoids with Human CYP2D6 Polymorphisms
Key Findings: This study investigated the interactions of four important highly prevalent CYP2D6 polymorphisms with selected phytocannabinoids and compared the binding capabilities as well as mechanisms of regulation within the endocannabinoid system.
Type of Study: Laboratory Study
Study Result: Inconclusive
Research Location(s): United States
Year of Pub: 2021
Cannabinoids Studied: Cannabichromene (CBC), Cannabidiol (CBD), Cannabigerol (CBG), Tetrahydrocannabinol (THC), Cannabinol (CBN), Anandamide (AEA), Tetrahydrocannabivarin (THCV)
Phytocannabinoid Source: Unspecified
Terpenes Studied: ß-Caryophyllene
Route of Administration: In vitro
Citation: Huff HC, et al. Differential Interactions of Selected Phytocannabinoids with Human CYP2D6 Polymorphisms. Biochemistry. 2021; 60:2749-2760. doi: 10.1021/acs.biochem.1c00158
Authors: Huff HC, Vasan A, Roy P, Kaul A, Tajkhorshid E, Das A
