PRIMARY STUDY
The plant cannabinoid Delta9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice
Key Findings: In this in vitro study delta(9)-tetrahydrocannabivarin (THCV) activates CB2 receptors and reduced signs of inflammation and inflammatory pain in mice. This mechanism of action appears to be through CB1 and/or CB2 receptor activation.
Type of Study: Laboratory Study
Study Result: Positive
Research Location(s): United Kingdom
Year of Pub: 2021
Cannabinoids Studied: Tetrahydrocannabivarin (THCV)
Phytocannabinoid Source: Cannabis Flower derived
Receptors Studied: CB1, CB2
Route of Administration: In vitro, Injection
Citation: Bolognini D, et al. The plant cannabinoid Delta9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice. Br J Pharmacol. 2010; 160:677-87. doi: 10.1111/j.1476-5381.2010.00756.x
Authors: Bolognini D, Costa B, Maione S, Comelli F, Marini P, Di Marzo V, Parolaro D, Ross RA, Gauson LA, Cascio MG, Pertwee RG
