PRIMARY STUDY
Symptom-relieving and neuroprotective effects of the phytocannabinoid Δ9-THCV in animal models of Parkinson's disease
Key Findings: Δ9-THCV (a CB1 antagonist) attenuated symptoms and demonstrated neuroprotective effects in an animal models of Parkinson's disease (posited to be initiated via modulation of glutamatergic transmissions.
Type of Study: Animal Study
Study Result: Positive
Research Location(s): Spain
Year of Pub: 2011
Cannabinoids Studied: Tetrahydrocannabivarin (THCV)
Phytocannabinoid Source: Unspecified
Receptors Studied: CB1
Ligands Studied: Glutamate
Citation: García C, et al. Symptom-relieving and neuroprotective effects of the phytocannabinoid Δ⁹-THCV in animal models of Parkinson's disease. Br J Pharmacol. 2011; 163:1495-506. doi: 10.1111/j.1476-5381.2011.01278.x
Authors: García C, Palomo-Garo C, García-Arencibia M, Ramos J, Pertwee R, Fernández-Ruiz J
