PRIMARY STUDY

Neural effects of cannabinoid CB1 neutral antagonist tetrahydrocannabivarin on food reward and aversion in healthy volunteers

Key Findings:  THCV (a CB1 antagonist) increases neural responding to rewarding and aversive stimuli in various portions of the brain with potential relevance to food behavior.

Type of Study:  Double Blind Clinical Trial

Study Sample Size:  24

Study Result:  Positive

Research Location(s):  United Kingdom

Year of Pub:  2015


Cannabinoids Studied:  Tetrahydrocannabivarin (THCV)

Phytocannabinoid Source:  Unspecified

Receptors Studied:  CB1

Dosage: 10mg THCV (single dose)




Citation:  Tudge L, et al. Neural effects of cannabinoid CB1 neutral antagonist tetrahydrocannabivarin on food reward and aversion in healthy volunteers. Int J Neuropsychopharmacol. 2014; 18:(unknown pages). doi: 10.1093/ijnp/pyu094

Authors:  Tudge L, Williams C, Cowen PJ, McCabe C