PRIMARY STUDY

Beneficial effects of the phytocannabinoid Δ 9-THCV in L-DOPA-induced dyskinesia in Parkinson's disease

Key Findings:  Data suggests a therapeutic potential (anti-dyskinesia) of Δ9-THCV. More specifically, THCV was able to delay the occurrence and to attenuate the magnitude of dyskinesia in an animal model of PD.

Type of Study:  Animal Study

Study Result:  Positive

Study Location(s):  Spain

Year of Pub:  2020


Cannabinoids Studied:  Tetrahydrocannabivarin (THCV)

Phytocannabinoid Source:  Unspecified

DOSING DETAILS   

Study Dosing Objective:  Effective Dose

Established Protocol:  Effective dose

Route of Administration:  Injection

Cannabinoid Ratio:  (THCV)   0    

Dosing Regimen:  THCV was administered i.p. at 2 mg/kg

Treatment Duration:  2 weeks

Clinical Relevance:  Data suggests a therapeutic potential (anti-dyskinesia) of Δ9-THCV. More specifically, THCV delayed the occurrence and attenuated the magnitude of dyskinesia in an animal model of PD.



Link to study