RELATED STUDY

Ingestion of a THC-Rich Cannabis Oil in People with Fibromyalgia: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Key Findings:  The authors conclude that cannabis-based therapeutics can be a low-cost and well-tolerated therapeutic option to mitigate signs and symptoms of fibromyalgia as well as improve their quality of life.

Type of Study:  Double Blind Clinical Trial

Study Sample Size:  17

Study Result:  Positive

Study Location(s):  Brazil

Year of Pub:  2020


Cannabinoids Studied:  Cannabichromene (CBC), Cannabidiol (CBD), Cannabigerol (CBG), Tetrahydrocannabinol (THC), Cannabinol (CBN), Tetrahydrocannabivarin (THCV)

Phytocannabinoid Source:  Cannabis Flower derived

Chemotype:  Chemotype I

Terpenes Studied:  ß-Caryophyllene, Myrcene, Pinene

DOSING DETAILS   

Study Dosing Objective:  Effective Dose

Established Protocol:  Effective dose

Route of Administration:  Oral (Ingestion)

Cannabinoid Ratio:  (THC : CBD)   61 : 1    

Dosage Form:  White Widow variety, at a 24.44-mg/mL concentration of THC and 0.51 mg/mL of CBD—at a proportion of ∼48/1 THC/CBD

Dosing Regimen:  Mean 3.6 drops a day (4.4 mg of THC and 0.08 mg of CBD)

Starting Dose:  One drop (∼1.22 mg of THC and 0.02 mg of CBD) a day

Titration:  Increases were titrated to effect

Treatment Duration:  8 weeks

Adverse Events:  There was no follow-up loss by unpleasant adverse effects.

Additional Notes:  Dose Titration



Link to study