RELATED STUDY

Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Δ⁹-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive-compulsive behaviour.

Key Findings:  CBD reduced OCD-like behavior in the test animals.

Type of Study:  Animal Study

Study Result:  Positive

Research Location(s):  United Kingdom

Year of Pub:  2012


Cannabinoids Studied:  Cannabidiol (CBD), Cannabigerol (CBG), Tetrahydrocannabivarin (THCV)

Phytocannabinoid Source:  Unspecified

Dosage: CBD (120 mg/kg, ip and oral)

Route of Administration:  Injection, Oral (Ingestion)




Citation:  Deiana S, et al. Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Δ⁹-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive-compulsive behaviour. Psychopharmacology (Berl). 2012; 219:859-73. doi: 10.1007/s00213-011-2415-0

Authors:  Deiana S, Watanabe A, Yamasaki Y, Amada N, Arthur M, Fleming S, Woodcock H, Dorward P, Pigliacampo B, Close S, Platt B, Riedel G