PRIMARY STUDY

Correlates of treatment engagement and client outcomes: results of a randomised controlled trial of nabiximols for the treatment of cannabis use disorder

Key Findings:  This secondary analysis from a study on the efficacy of using cannabinoid medications, namely nabiximols, to treat cannabis use disorder (CUD) found that counseling plus pharmacotherapy had the best improvement in treatment outcomes. Other findings were that younger, males, and those with sleep concerns benefitted more from additional treatment services.

Type of Study:  Double Blind Clinical Trial

Study Sample Size:  128

Study Result:  Positive

Research Location(s):  Australia

Year of Pub:  2022


Cannabinoids Studied:  Cannabidiol (CBD), Tetrahydrocannabinol (THC), Pharma THC:CBD

Phytocannabinoid Source:  Not Applicable

Chemotype:  Chemotype II

Sub-Ratio: 2.7 mg THC : 2.5 mg CBD

Dosage: Up to 32 oromucosal sprays daily, each spray containing 2.7 mg THC and 2.5 mg CBD

Route of Administration:  Sublingual/Oromucosal




Citation:  Mills L, et al. Correlates of treatment engagement and client outcomes: results of a randomised controlled trial of nabiximols for the treatment of cannabis use disorder. Subst Abuse Treat Prev Policy. 2022; 17:67. doi: 10.1186/s13011-022-00493-z

Authors:  Mills L, Dunlop A, Montebello M, Copeland J, Bruno R, Jefferies M, Mcgregor I, Lintzeris N