Key Findings:  This review explains the anti-inflammatory properties of the endocannabinoid system (ECS), especially CB2 receptors, against inflammatory lung injury and viral infections as in COVID-19. It concludes that there may be useful targets in the ECS managing COVID-19 via their anti-inflammatory action and the suppression of inflammatory cytokines and signaling pathways.
Type of Study:  Meta-analysis
Study Result:  Positive
Research Location(s):  Australia, Austria, Egypt, Iraq
Year of Pub:  2022
Cannabinoids Studied:  Cannabidiol (CBD), Tetrahydrocannabinol (THC), Endocannabinoid (unspecified)
Phytocannabinoid Source:  Unspecified
Chemotype:  Chemotype I, Chemotype III
Receptors Studied:  CB1, CB2, GPCR
Citation:  Al-Kuraishy HM, et al. Cannabinoids Receptors in COVID-19: Perpetrators and Victims. Curr Med Chem. 2023; 30:3832-3845. doi: 10.2174/0929867329666220829145029
Authors:  Al-Kuraishy HM, Al-Gareeb AI, Alexiou A, Batiha GE