PRIMARY STUDY

Cannabinoids receptors in Covid-19: Perpetrators and victims

Key Findings:  This review explains the anti-inflammatory properties of the endocannabinoid system (ECS), especially CB2 receptors, against inflammatory lung injury and viral infections as in COVID-19. It concludes that there may be useful targets in the ECS managing COVID-19 via their anti-inflammatory action and the suppression of inflammatory cytokines and signaling pathways.

Type of Study:  Meta-analysis

Study Result:  Positive

Research Location(s):  Australia, Austria, Egypt, Iraq

Year of Pub:  2022


Cannabinoids Studied:  Cannabidiol (CBD), Tetrahydrocannabinol (THC), Endocannabinoid (unspecified)

Phytocannabinoid Source:  Unspecified

Chemotype:  Chemotype I, Chemotype III

Receptors Studied:  CB1, CB2, GPCR




Citation:  Al-Kuraishy HM, et al. Cannabinoids Receptors in COVID-19: Perpetrators and Victims. Curr Med Chem. 2023; 30:3832-3845. doi: 10.2174/0929867329666220829145029

Authors:  Al-Kuraishy HM, Al-Gareeb AI, Alexiou A, Batiha GE