PRIMARY STUDY

Alpha-terpineol prevents myocardial damage against isoproterenol-MI induced in Wistar-Kyoto rats: new possible to promote cardiovascular integrity

Key Findings:  Resulting data shows that pretreatment with alpha-terpineol significantly inhibited the effects of ISO-induced mortality rates, cardiac marker enzymes, tachycardia, hypertrophy, myocardium necrosis, edema, hemorrhagic areas, infiltration of inflammatory cells like lymphocytes, and increased myocardial infarct size in the test animals.

Type of Study:  Animal Study

Study Result:  Positive

Research Location(s):  Brazil

Year of Pub:  2022


Cannabinoids Studied: 

Phytocannabinoid Source:  Not Applicable

Terpenes Studied:  Terpineol




Citation:  Paulino ET, et al. Alpha-terpineol prevents myocardial damage against isoproterenol-MI induced in Wistar-Kyoto rats: new possible to promote cardiovascular integrity. Life Sci. 2022; 290:120087. doi: 10.1016/j.lfs.2021.120087

Authors:  Paulino ET, Rodrigues AKBF, Machado MLDP, de Oliveira KRV, Bernardino AC, Quintans-Júnior LJ, Oliveira AP, Ribeiro ÊAN