PRIMARY STUDY
Cannabis use, oral dysbiosis, and neurological disorders
Key Findings: This review suggests that there is a link between smoking cannabis and neurological abnormalities, immunity, and oral microbiome through immunosuppressive properties of cannabinoids and possible microbial translocation via the oral-brain axis.
Type of Study: Meta-analysis
Study Result: Negative
Research Location(s): United States
Year of Pub: 2024
Cannabinoids Studied: Cannabidiol (CBD), Tetrahydrocannabinol (THC), Cannabinoid (unspecified), Microbiome
Phytocannabinoid Source: Not Applicable
Receptors Studied: CB1, CB2, TRPV2, TRPV4, TRPM8, GPCR, TRPs
Ligands Studied: Serotonin, Pro-inflammatory cytokines
Route of Administration: Inhalation
Citation: Hazzard AA, McCrorey M, Salman T, Johnson DE, Luo Z, Fu X, Keegan AP, Benitez A, Fitting S, Jiang W. Cannabis use, oral dysbiosis, and neurological disorders. NeuroImmune Pharm Ther. 2024 Aug 9;3(3-4):183-193. doi: 10.1515/nipt-2024-0012. PMID: 39741560; PMCID: PMC11683879.
