PRIMARY STUDY

The Effects of β-myrcene on Simulated Driving and Divided Attention: A Double-Blind, Placebo-Controlled, Crossover Pilot Study

Key Findings:  β-myrcene, thought to be the sedating terpene in cannabis, was associated with reduced speed control and increased errors on a simulated driving test, consistent with the hypothesis that β-myrcene impairs driving.

Type of Study:  Double Blind Clinical Trial

Study Sample Size:  10

Study Result:  Negative

Research Location(s):  United States

Year of Pub:  2023


Cannabinoids Studied:  Cannabinoid (unspecified)

Phytocannabinoid Source:  Not Applicable

Terpenes Studied:  Myrcene

DOSING DETAILS   

Study Dosing Objective:  Safety Profile

Dosage Form:  capsule

Dosing Regimen:  15 mg of pure β-myrcene versus a canola oil control

Clinical Relevance:  β-myrcene, was associated with reduced speed control and increased errors on a simulated driving test.

Adverse Events:  reduced speed control, increased cognitive errors

Additional Notes:  Cross-Over




Citation:  Johnson MB, et al. The Effects of β-myrcene on Simulated Driving and Divided Attention: A Double-Blind, Placebo-Controlled, Crossover Pilot Study. Cannabis. 2023; 6:9-19. doi: 10.26828/cannabis/2023.01.002

Authors:  Johnson MB, McKnight S, Taylor EP, Mechtler L, Ralyea CC