PRIMARY STUDY
Cannabidiol Interferes with Establishment of Δ 9-Tetrahydrocannabinol-Induced Nausea Through a 5-HT 1A Mechanism
Key Findings: Data revealed that CBD reduced the effects of THC-induced nausea. In addition CBD inhibited THC-induced elevation in corticosterone.
Type of Study: Animal Study
Study Result: Positive
Research Location(s): Canada
Year of Pub: 2022
Cannabinoids Studied: Cannabidiol (CBD)
Phytocannabinoid Source: Unspecified
Chemotype: Chemotype III
Ligands Studied: Serotonin
Route of Administration: Injection
Citation: DeVuono MV, et al. Cannabidiol Interferes with Establishment of Δ9-Tetrahydrocannabinol-Induced Nausea Through a 5-HT1A Mechanism. Cannabis Cannabinoid Res. 2022; 7:58-64. doi: 10.1089/can.2020.0083
Authors: DeVuono MV, La Caprara O, Petrie GN, Limebeer CL, Rock EM, Hill MN, Parker LA
