Key Findings:  The authors describe the case of a 12-year-old boy with severe seizures due to a pathogenic KCNB1 variant refractory to anti-epileptics. At age 11, he was started on highly purified CBD and has been seizure-free for 18 months. In addition, the patient showed improvements in EEG and social skills.
Type of Study:  Meta-analysis
Study Sample Size:  1
Study Result:  Positive
Research Location(s):  Italy, United States
Year of Pub:  2024
Cannabinoids Studied:  Cannabidiol (CBD)
Phytocannabinoid Source:  Unspecified
Chemotype:  Chemotype III
Citation:  Ferrera G, et al. Continuous spike-wave of slow sleep in a patient with KCNB1-related epilepsy responsive to highly purified cannabidiol: a case report and comparison with literature. Neurocase. 2024; 30:68-72. doi: 10.1080/13554794.2024.2354952
Authors:  Ferrera G, Ricci E, Peron A, Parrini E, Vignoli A, Canevini MP