Key Findings:  Two experiments show promise for behavioral improvement using ultramicronized PEA with luteolin in a mouse model of autism and a 10-year old patient with ASD.
Type of Study:  Meta-analysis
Study Sample Size:  1
Study Result:  Positive
Research Location(s):  Italy, United States
Year of Pub:  2016
Cannabinoids Studied:  Palmitoylethanolamide (PEA)
Phytocannabinoid Source:  Not Applicable
Ligands Studied:  Anti-inflammatory cytokines
Citation:  Bertolino B, et al. Beneficial Effects of Co-Ultramicronized Palmitoylethanolamide/Luteolin in a Mouse Model of Autism and in a Case Report of Autism. CNS Neurosci Ther. 2017; 23:87-98. doi: 10.1111/cns.12648
Authors:  Bertolino B, Crupi R, Impellizzeri D, Bruschetta G, Cordaro M, Siracusa R, Esposito E, Cuzzocrea S