PRIMARY STUDY
Deficiency of autism-related Scn2a gene in mice disrupts sleep patterns and circadian rhythms
Key Findings: The authors we identified HU-211 as a putative glutamate receptor modulator, that can partially reverse the sleep disturbance in the test animals.
Type of Study: Animal Study
Study Result: Positive
Research Location(s): China, United States
Year of Pub: 2022
Cannabinoids Studied: HU-x Synthetic Cannabinoids
Phytocannabinoid Source: Not Applicable
Ligands Studied: Glutamate
Citation: Ma Z, et al. Deficiency of autism-related Scn2a gene in mice disrupts sleep patterns and circadian rhythms. Neurobiol Dis. 2022; 168:105690. doi: 10.1016/j.nbd.2022.105690
Authors: Ma Z, Eaton M, Liu Y, Zhang J, Chen X, Tu X, Shi Y, Que Z, Wettschurack K, Zhang Z, Shi R, Chen Y, Kimbrough A, Lanman NA, Schust L, Huang Z, Yang Y
