RELATED STUDY
Cannabidiol Exposure During the Mouse Adolescent Period Is Without Harmful Behavioral Effects on Locomotor Activity, Anxiety, and Spatial Memory
Key Findings: Prolonged exposure to cannabidiol (CBD) in adolescent mice did not lead to adverse behaviors like mobility, anxiety, and spatial learning, in adulthood. In some conditions in this study, CBD actually showed improved learning and showed weight gain in males.
Type of Study: Animal Study
Study Sample Size: 26
Study Result: Positive
Research Location(s): United States
Year of Pub: 2021
Cannabinoids Studied: Cannabidiol (CBD)
Phytocannabinoid Source: Isolate
Chemotype: Chemotype III
DOSING DETAILS 
Study Dosing Objective: Safety Profile
Established Protocol: Optimal dose
Route of Administration: Injection
Cannabinoid Ratio: (CBD) 0 
Dosage Form: CBD isolate (>98% purity)
Dosing Regimen: CBD 20 mg/kg i.p. twice a day
Treatment Duration: 21 days
Citation: Kaplan JS, et al. Cannabidiol Exposure During the Mouse Adolescent Period Is Without Harmful Behavioral Effects on Locomotor Activity, Anxiety, and Spatial Memory. Front Behav Neurosci. 2021; 15:711639. doi: 10.3389/fnbeh.2021.711639
Authors: Kaplan JS, Wagner JK, Reid K, McGuinness F, Arvila S, Brooks M, Stevenson H, Jones J, Risch B, McGillis T, Budinich R, Gambell E, Predovich B
