Key Findings:  The goal of this pilot study was to assess the feasibility of conducting a randomized controlled trial of cannabidiol in treating children with severe behavioral and intellectual disabilities. Overall the efficacy signal favored active drug.
Type of Study:  Double Blind Clinical Trial
Study Sample Size:  8
Study Result:  Positive
Research Location(s):  Australia
Year of Pub:  2021
Cannabinoids Studied:  Cannabidiol (CBD)
Phytocannabinoid Source:  Cannabis Flower derived
Chemotype:  Chemotype III
Dosage: Cannabidiol (20-1000 mg/kg/day)
Citation:  Efron D, et al. A pilot randomised placebo-controlled trial of cannabidiol to reduce severe behavioural problems in children and adolescents with intellectual disability. Br J Clin Pharmacol. 2021; 87:436-446. doi: 10.1111/bcp.14399
Authors:  Efron D, Freeman JL, Cranswick N, Payne JM, Mulraney M, Prakash C, Lee KJ, Taylor K, Williams K