PRIMARY STUDY
Pharmacological inhibition of the primary endocannabinoid producing enzyme, DGL-α, induces autism spectrum disorder-like and co-morbid phenotypes in adult C57BL/J mice
Key Findings: Data suggests that pharmacological inhibition of DAGL-alpha prouced a number of behavioral domains deficits associated with autism.
Type of Study: Animal Study
Study Result: Positive
Research Location(s): United States
Year of Pub: 2021
Cannabinoids Studied: Other Related Compounds
Phytocannabinoid Source: Not Applicable
Citation: Fyke W, et al. Pharmacological inhibition of the primary endocannabinoid producing enzyme, DGL-α, induces autism spectrum disorder-like and co-morbid phenotypes in adult C57BL/J mice. Autism Res. 2021; 14:1375-1389. doi: 10.1002/aur.2520
Authors: Fyke W, Alarcon JM, Velinov M, Chadman KK
