PRIMARY STUDY

Role of the endocannabinoid system in neurological disorders.

Key Findings:  Collectively, the findings to date indicate that the eCB system plays a key role in the pathophysiology of ASD and can provide new insights into potential interventions and rehabilitation strategies for ASD.

Type of Study:  Meta-analysis

Study Result:  Positive

Research Location(s):  China

Year of Pub:  2018


Cannabinoids Studied:  Tetrahydrocannabinol (THC), Anandamide (AEA), Fatty Acid Amide Hydrolase (FAAH), 2-Arachidonoyl Glycerol (2-AG), Monoacylglycerol Lipase (MAGL), Endocannabinoid (unspecified), Other Related Compounds

Phytocannabinoid Source:  Not Applicable

Receptors Studied:  TRPV1, GPCR, PPARs

Ligands Studied:  GABA




Citation:  Zou M, et al. Role of the endocannabinoid system in neurological disorders. Int J Dev Neurosci. 2019; 76:95-102. doi: 10.1016/j.ijdevneu.2019.03.002

Authors:  Zou M, Li D, Li L, Wu L, Sun C