PRIMARY STUDY
Symphony of the gut microbiota and endocannabinoidome: a molecular and functional perspective
Key Findings: This literature review discusses the strong interactions between the gut microbiota and the endocannabinoidome (eCBome) and the role of diet and exercise in regulating this interaction.
Type of Study: Meta-analysis
Study Result: Positive
Research Location(s): China
Year of Pub: 2025
Cannabinoids Studied: Anandamide (AEA), 2-Arachidonoyl Glycerol (2-AG), Monoacylglycerol Lipase (MAGL), Endocannabinoid (unspecified), Palmitoylethanolamide (PEA), Microbiome, Exercise, Oleoylethanolamide (OEA)
Phytocannabinoid Source: Not Applicable
Receptors Studied: CB1, CB2, PPAR - Alpha, PPAR - Gamma, GPCR, TRPs, PPARs
Ligands Studied: Dopamine, Serotonin
Citation: Wang Y, Guo J, Mao Z, Chen Y. Symphony of the gut microbiota and endocannabinoidome: a molecular and functional perspective. Front Cell Infect Microbiol. 2025 Mar 26;15:1566290. doi: 10.3389/fcimb.2025.1566290. PMID: 40207053; PMCID: PMC11979265.
