Key Findings:  This rat model of post-operative intestinal adhesions and the therapeutic effects of Kangnian (KN) decoction, proved that KN reduces intestinal injury, downregulates inflammation, and alleviates intestinal adhesions, via 75 differently expressed proteins primarily involved in Valine, leucine, and isoleucine degradation, the MAPK signaling pathway, and retrograde endocannabinoid signaling
Type of Study:  Animal Study
Study Result:  Positive
Research Location(s):  China
Year of Pub:  2024
Cannabinoids Studied:  Endocannabinoid (unspecified)
Phytocannabinoid Source:  Not Applicable
Citation:  Jin L, et al. LC-MS/MS-based metabolomics and proteomics reveal the intervention of Kangnian decoction on the postoperative intestinal adhesion of rats. Front Pharmacol. 2024; 15:1382760. doi: 10.3389/fphar.2024.1382760
Authors:  Jin L, Zhao Y, Qian X, Pan L, Chen L, Feng J, Liu X, Lu X