RELATED STUDY

LC-MS/MS-based metabolomics and proteomics reveal the intervention of Kangnian decoction on the postoperative intestinal adhesion of rats

Key Findings:  This rat model of post-operative intestinal adhesions and the therapeutic effects of Kangnian (KN) decoction, proved that KN reduces intestinal injury, downregulates inflammation, and alleviates intestinal adhesions, via 75 differently expressed proteins primarily involved in Valine, leucine, and isoleucine degradation, the MAPK signaling pathway, and retrograde endocannabinoid signaling

Type of Study:  Animal Study

Study Result:  Positive

Research Location(s):  China

Year of Pub:  2024


Cannabinoids Studied:  Endocannabinoid (unspecified)

Phytocannabinoid Source:  Not Applicable




Citation:  Jin L, et al. LC-MS/MS-based metabolomics and proteomics reveal the intervention of Kangnian decoction on the postoperative intestinal adhesion of rats. Front Pharmacol. 2024; 15:1382760. doi: 10.3389/fphar.2024.1382760

Authors:  Jin L, Zhao Y, Qian X, Pan L, Chen L, Feng J, Liu X, Lu X