RELATED STUDY
Cannabidiol safety considerations: Development of a potential acceptable daily intake value and recommended upper intake limits for dietary supplement use
Key Findings: Using data from published human clinical trials and toxicity studies in animal models this author identified safe and acceptable daily dietary supplementation levels of cannabidiol (CBD) of 0.43 mg/kg of body weight per day for the general population including children, and an upper limit (UL) of 70 mg/d, and 60-100mg/day for healthy adults not attempting childbearing.
Type of Study: Clinical Trial
Study Result: Positive
Research Location(s): United States
Year of Pub: 2023
Cannabinoids Studied: Cannabidiol (CBD), Tetrahydrocannabinol (THC), Pharma THC:CBD, Pharma CBD, Diet
Phytocannabinoid Source: Isolate
Chemotype: Chemotype III
Route of Administration: Oral (Ingestion)
Citation: Henderson RG, et al. Cannabidiol safety considerations: Development of a potential acceptable daily intake value and recommended upper intake limits for dietary supplement use. Regul Toxicol Pharmacol. 2023; 144:105482. doi: 10.1016/j.yrtph.2023.105482
Authors: Henderson RG, Vincent M, Rivera BN, Bonn-Miller MO, Doepker C
