RELATED STUDY
Oral administration of d-limonene controls inflammation in rat colitis and displays anti-inflammatory properties as diet supplementation in humans.
Key Findings: Limonene indeed demonstrates significant anti-inflammatory effects both in vivo and in vitro. Protective effects on the epithelial barrier and decreased cytokines are involved, suggesting a beneficial role of d-Limonene as diet supplement in reducing inflammation.
Type of Study: Animal Study
Study Result: Positive
Research Location(s): France
Year of Pub: 2013
Cannabinoids Studied:
Phytocannabinoid Source: Not Applicable
Terpenes Studied: Limonene
Ligands Studied: Anti-inflammatory cytokines, Pro-inflammatory cytokines
Dosage: d-Limonene (10mg/kg)
Route of Administration: Oral (Ingestion)
Citation: d'Alessio PA, et al. Oral administration of d-limonene controls inflammation in rat colitis and displays anti-inflammatory properties as diet supplementation in humans. Life Sci. 2013; 92:1151-6. doi: 10.1016/j.lfs.2013.04.013
Authors: d'Alessio PA, Ostan R, Bisson JF, Schulzke JD, Ursini MV, Béné MC
