RELATED STUDY

Maternal administration of cannabidiol promotes an anti-inflammatory effect on the intestinal wall in a gastroschisis rat model

Key Findings:  Pregnant rats were given cannabidiol (CBD) in a model of gastroschisis (GS) to evaluate potential anti-inflammatory, neuroprotective, and antioxidant properties. Results found that CBD had beneficial effects on intestinal loops and decreased anti-inflammatory markers in GS rats.

Type of Study:  Animal Study

Study Sample Size:  40

Study Result:  Positive

Research Location(s):  Brazil

Year of Pub:  2018


Cannabinoids Studied:  Cannabidiol (CBD)

Phytocannabinoid Source:  Not Applicable

Chemotype:  Chemotype III

Route of Administration:  Injection




Citation:  Callejas GH, et al. Maternal administration of cannabidiol promotes an anti-inflammatory effect on the intestinal wall in a gastroschisis rat model. Braz J Med Biol Res. 2018; 51:e7132. doi: 10.1590/1414-431X20177132

Authors:  Callejas GH, Figueira RL, Gonçalves FLL, Volpe FAP, Zuardi AW, Crippa JA, Hallak JE, Sbragia L