Key Findings:  This overview dives into the pharmacological and physiologic effects of the acidic form of cannabigerol (CBG), CBDA, and synthetic CBG. Some of the available research suggests it may be useful in inflammatory conditions, and possess anti-tumor, and anti-anxiety properties as well as positive skin healing and appetite stimulation abilities.
Type of Study:  Meta-analysis
Study Result:  Positive
Research Location(s):  Italy
Year of Pub:  2022
Cannabinoids Studied:  Cannabichromene (CBC), Cannabidiol (CBD), Cannabigerol (CBG), Tetrahydrocannabinol (THC), Cannabinol (CBN), Cannabigerolic Acid (CBG-a), JWH-x Synthetic Cannabinoids, Anandamide (AEA), Synthetic Cannabinoid (unspecified), Endocannabinoid (unspecified), Delta-8-THC
Phytocannabinoid Source:  Not Applicable
Receptors Studied:  CB1, CB2, PPAR - Gamma, TRPs, PPARs
Ligands Studied:  Acetylcholine, Dopamine, Serotonin
Route of Administration:  In vitro, Injection
Citation:  Calapai F, et al. Pharmacological Aspects and Biological Effects of Cannabigerol and Its Synthetic Derivatives. Evid Based Complement Alternat Med. 2022; 2022:3336516. doi: 10.1155/2022/3336516
Authors:  Calapai F, Cardia L, Esposito E, Ammendolia I, Mondello C, Lo Giudice R, Gangemi S, Calapai G, Mannucci C