RELATED STUDY

Cannabis induces a clinical response in patients with Crohn's disease: a prospective placebo-controlled study

Key Findings:  Complete remission (Crohn's Disease Activity Index (CDAI) score, 100) was observed in 10 of 11 subjects in the cannabis group and 4 of 10 in the placebo group. Three patients in the cannabis group were weaned from steroid dependency. Subjects receiving cannabis reported improved appetite and sleep, with no significant side effects.

Type of Study:  Double Blind Clinical Trial

Study Sample Size:  21

Study Result:  Positive

Study Location(s):  Israel

Year of Pub:  2013


Cannabinoids Studied:  Tetrahydrocannabinol (THC)

Phytocannabinoid Source:  Cannabis Flower derived

Chemotype:  Chemotype I

DOSING DETAILS   

Study Dosing Objective:  Effective Dose

Established Protocol:  Effective dose

Route of Administration:  Inhalation

Cannabinoid Ratio:  (THC)   0    

Dosage Form:  Each cigarette contained 0.5 g of dried cannabis flowers (flowers have a higher THC content than leaves), corresponding to 115 mg THC

Dosing Regimen:  THC (115 mg) or placebo twice a day

Treatment Duration:  8 weeks

Clinical Relevance:  A short course of THC-rich cannabis produced significant clinical, steroid-free benefits.



Link to study