Key Findings:  Complete remission (Crohn's Disease Activity Index (CDAI) score, 100) was observed in 10 of 11 subjects in the cannabis group and 4 of 10 in the placebo group. Three patients in the cannabis group were weaned from steroid dependency. Subjects receiving cannabis reported improved appetite and sleep, with no significant side effects.
Type of Study:  Double Blind Clinical Trial
Study Sample Size:  21
Study Result:  Positive
Study Location(s):  Israel
Year of Pub:  2013
Cannabinoids Studied:  Tetrahydrocannabinol (THC)
Phytocannabinoid Source:  Cannabis Flower derived
Chemotype:  Chemotype I
DOSING DETAILS   
Study Dosing Objective:  Effective Dose
Established Protocol:  Effective dose
Route of Administration:  Inhalation
Cannabinoid Ratio:  (THC)   0    
Dosage Form:  Each cigarette contained 0.5 g of dried cannabis flowers (flowers have a higher THC content than leaves), corresponding to 115 mg THC
Dosing Regimen:  THC (115 mg) or placebo twice a day
Treatment Duration:  8 weeks
Clinical Relevance:  A short course of THC-rich cannabis produced significant clinical, steroid-free benefits.