PRIMARY STUDY
New FAAH inhibitors based on 3-carboxamido-5-aryl-isoxazole scaffold that protect against experimental colitis
Key Findings: This report identifies a compound that inhibits FAAH activity and reduces bowel inflammation.
Type of Study: Animal Study
Study Result: Positive
Research Location(s): France
Year of Pub: 2011
Cannabinoids Studied: Anandamide (AEA), Fatty Acid Amide Hydrolase (FAAH), Endocannabinoid (unspecified)
Phytocannabinoid Source: Not Applicable
Citation: Andrzejak V, et al. New FAAH inhibitors based on 3-carboxamido-5-aryl-isoxazole scaffold that protect against experimental colitis. Bioorg Med Chem. 2011; 19:3777-86. doi: 10.1016/j.bmc.2011.04.057
Authors: Andrzejak V, Muccioli GG, Body-Malapel M, El Bakali J, Djouina M, Renault N, Chavatte P, Desreumaux P, Lambert DM, Millet R
