RELATED STUDY
Low-Dose Cannabidiol Is Safe but Not Effective in the Treatment for Crohn's Disease, a Randomized Controlled Trial
Key Findings: In this study of moderately active Crohn's disease, CBD was safe but had no beneficial effects. This could be due to lack of effect of CBD on Crohn's disease, but could also be due to the small dose of CBD, the small number of patients in the study, or the lack of the necessary synergism with other cannabinoids. Further investigation is warranted.
Type of Study: Double Blind Clinical Trial
Study Sample Size: 20
Study Result: Inconclusive
Research Location(s): Israel
Year of Pub: 2017
Cannabinoids Studied: Cannabidiol (CBD)
Phytocannabinoid Source: Unspecified
Chemotype: Chemotype III
Sub-Ratio: 0:1 (THC:CBD)
DOSING DETAILS 
Study Dosing Objective: Effective Dose
Established Protocol: No effective dose
Route of Administration: Oral (Ingestion)
Cannabinoid Ratio: (CBD) 0
Dosing Regimen: CBD (10 mg) or placebo 2x daily
Treatment Duration: 8 weeks
Clinical Relevance: For Crohn's disease, CBD was safe but had no beneficial effects.
Adverse Events: No side effects were observed.
Citation: Naftali T, et al. Low-Dose Cannabidiol Is Safe but Not Effective in the Treatment for Crohn's Disease, a Randomized Controlled Trial. Dig Dis Sci. 2017; 62:1615-1620. doi: 10.1007/s10620-017-4540-z
Authors: Naftali T, Mechulam R, Marii A, Gabay G, Stein A, Bronshtain M, Laish I, Benjaminov F, Konikoff FM
