PRIMARY STUDY

Electroacupuncture Reduces Anxiety Associated With Inflammatory Bowel Disease By Acting on Cannabinoid CB1 Receptors in the Ventral Hippocampus in Mice

Key Findings:  The authors concluded that we modulation of CB1 in both GABAergic neurons and glutamatergic neurons are involved in the inhibitory effect of electroacupuncture on anxiety (but not visceral pain in IBD in the test animals).

Type of Study:  Animal Study

Study Result:  Positive

Research Location(s):  China, United States

Year of Pub:  2022


Cannabinoids Studied:  Acupuncture (TCM)

Phytocannabinoid Source:  Not Applicable

Receptors Studied:  CB1

Ligands Studied:  GABA, Glutamate




Citation:  Hu XF, et al. Electroacupuncture Reduces Anxiety Associated With Inflammatory Bowel Disease By Acting on Cannabinoid CB1 Receptors in the Ventral Hippocampus in Mice. Front Pharmacol. 2022; 13:919553. doi: 10.3389/fphar.2022.919553

Authors:  Hu XF, Zhang H, Yu LL, Ge WQ, Zhan-Mu OY, Li YZ, Chen C, Hou TF, Xiang HC, Li YH, Su YS, Jing XH, Cao J, Pan HL, He W, Li M