Key Findings:  This review concludes that there is increasing evidence that early exposure and long-term use of cannabis may lead to an increase in undesirable health conditions and side effects. These include dependency, cognitive changes, behavioral and psychological changes, cardiovascular and fertility problems, and some types of cancers.
Type of Study:  Meta-analysis
Study Result:  Negative
Research Location(s):  Canada
Year of Pub:  2022
Cannabinoids Studied:  Cannabidiol (CBD), Tetrahydrocannabinol (THC), Cannabinoid (unspecified), Pharma CBD
Phytocannabinoid Source:  Unspecified
Receptors Studied:  CB1, CB2
Ligands Studied:  GABA, Testosterone
Citation:  Bannigan P, et al. Shifting the Paradigm on Cannabis Safety. Cannabis Cannabinoid Res. 2022; 7:3-10. doi: 10.1089/can.2020.0003
Authors:  Bannigan P, Evans JC, Allen C