RELATED STUDY

Candidate Therapeutics by Screening for Multitargeting Ligands: Combining the CB2 Receptor With CB1, PPARγ and 5-HT4 Receptors

Key Findings:  This theoretical study using the Iterative Stochastic Elimination (ISE) algorithm aimed to assess different combinations of cannabinoid-targeting agents, both agonists or antagonists. One main finding was that CB2R agonist plus PPARγ or 5-HT4R agonist could provide therapeutic use in treating Inflammatory Bowel Disease (IBD).