RELATED STUDY
Endocannabinoid Modulation in Neurodegenerative Diseases: In Pursuit of Certainty
Key Findings: This extensive review covers the endocannabinoid system, specifically cannabinoid receptors, and the effect of exogenous cannabinoids on neuroinflammatory diseases such as Alzheimer's, Huntington's, Parkinson's, and Multiple Sclerosis.
Type of Study: Meta-analysis
Study Result: Positive
Research Location(s): Ireland, Romania
Year of Pub: 2022
Cannabinoids Studied: Cannabidiol (CBD), Tetrahydrocannabinol (THC), AM-x Synthetic Cannabinoids, JWH-x Synthetic Cannabinoids, HU-x Synthetic Cannabinoids, WIN-x Synthetic Cannabinoids, Anandamide (AEA), Fatty Acid Amide Hydrolase (FAAH), 2-Arachidonoyl Glycerol (2-AG), Monoacylglycerol Lipase (MAGL), Endocannabinoid (unspecified), Pharma THC
Phytocannabinoid Source: Not Applicable
Receptors Studied: CB1, CB2, TRPV1, PPAR - Gamma, GPCR
Ligands Studied: Dopamine, Epinephrine, Glutamate, Norepinephrine, Serotonin, Pro-inflammatory cytokines
Citation: Vasincu A, et al. Endocannabinoid Modulation in Neurodegenerative Diseases: In Pursuit of Certainty. Biology (Basel). 2022; 11:(unknown pages). doi: 10.3390/biology11030440
Authors: Vasincu A, Rusu RN, Ababei DC, Larion M, Bild W, Stanciu GD, Solcan C, Bild V
