Key Findings:  the authors posit that cannabinoids (e.g. 2-AG, Anandamide, CBD, THC) can cause hyperemesis and cyclic vomiting syndrome on one hand, but may also reduce gastrointestinal, pancreatic, or hepatic inflammation, as well as a treatment for motility, abdominal pain, and functional abdominal disorders.
Type of Study:  Meta-analysis
Study Result:  Inconclusive
Research Location(s):  United States
Year of Pub:  2021
Cannabinoids Studied:  Cannabidiol (CBD), Tetrahydrocannabinol (THC), Anandamide (AEA), Fatty Acid Amide Hydrolase (FAAH), 2-Arachidonoyl Glycerol (2-AG), Monoacylglycerol Lipase (MAGL)
Phytocannabinoid Source:  Unspecified
Citation:  Maselli DB and Camilleri M. Pharmacology, Clinical Effects, and Therapeutic Potential of Cannabinoids for Gastrointestinal and Liver Diseases. Clin Gastroenterol Hepatol. 2021; 19:1748-1758.e2. doi: 10.1016/j.cgh.2020.04.020
Authors:  Maselli DB, Camilleri M