PRIMARY STUDY
Cannabis is associated with clinical but not endoscopic remission in ulcerative colitis: A randomized controlled trial
Key Findings: While not significantly affecting anti-inflammatory markers data shows that treatment with a cannabis chemotype I (abundant in THC) produced clinical remission and improved quality of life in patients with mild to moderately active ulcerative colitis.
Type of Study: Double Blind Clinical Trial
Study Sample Size: 32
Study Result: Positive
Research Location(s): Israel
Year of Pub: 2019
Cannabinoids Studied: Tetrahydrocannabinol (THC), Cannabinoid (unspecified)
Phytocannabinoid Source: Cannabis Flower derived
Chemotype: Chemotype I
Dosage: Patients received either cigarettes containing 0.5 g of dried cannabis flowers with 80mg THC or placebo x 8 weeks.
Route of Administration: Inhalation
Citation: Naftali T, et al. Cannabis is associated with clinical but not endoscopic remission in ulcerative colitis: A randomized controlled trial. PLoS One. 2021; 16:e0246871. doi: 10.1371/journal.pone.0246871
Authors: Naftali T, Bar-Lev Schleider L, Scklerovsky Benjaminov F, Konikoff FM, Matalon ST, Ringel Y
