PRIMARY STUDY

Modulatory role of the endocannabinoidome in the pathophysiology of the gastrointestinal tract

Key Findings:  This review introduces the expanded endocannabinoid system (“endocannabinoidome”) and highlights its complex interactions with gut microbiota in regulating gastrointestinal, inflammatory, and metabolic processes, identifying novel receptor targets for therapeutic intervention in disorders such as inflammatory bowel disease, obesity, and type 2 diabetes.